Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.44 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11523022 | 1.00 | GRIA1 (0.44) | GRIA1GRIA2GRIA3MGLLHRH3 | |
| SCHEMBL11522999 | 0.99 | GRIA1 (0.45) | GRIA1GRIA2GRIA3MGLLHRH3 | |
| SCHEMBL11523002 | 0.99 | GRIA1 (0.45) | GRIA1GRIA2GRIA3MGLLHRH3 | |
| SCHEMBL11524530 | 0.95 | GRIA1 (0.46) | GRIA1GRIA2GRIA3MGLLHRH3 | |
| SCHEMBL11524533 | 0.95 | GRIA1 (0.46) | GRIA1GRIA2GRIA3MGLLHRH3 | |
| SCHEMBL11524026 | 0.90 | GRIA1 (0.47) | GRIA1GRIA2GRIA3HRH3USP30 | |
| SCHEMBL11524029 | 0.90 | GRIA1 (0.47) | GRIA1GRIA2GRIA3HRH3USP30 | |
| SCHEMBL8433659 | 0.88 | MGLL (0.48) | MGLLHRH3TSHRHSD17B10KDM4E | |
| SCHEMBL8432085 | 0.88 | MGLL (0.48) | MGLLHRH3TSHRHSD17B10KDM4E | |
| SCHEMBL8432091 | 0.88 | MGLL (0.48) | MGLLHRH3TSHRHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154697-A | Liquid crystalline hexahydroterphenyl derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1979-05-15 | — | — | US | disclosed |