Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.41 |
| ▸ | HRH2 | P25021 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11524530 | 1.00 | GRIA1 (0.46) | GRIA1GRIA2GRIA3HRH3USP30 | |
| SCHEMBL11523002 | 0.96 | GRIA1 (0.45) | GRIA1GRIA2GRIA3HRH3USP30 | |
| SCHEMBL11522999 | 0.96 | GRIA1 (0.45) | GRIA1GRIA2GRIA3HRH3USP30 | |
| SCHEMBL11523022 | 0.95 | GRIA1 (0.44) | GRIA1GRIA2GRIA3HRH3USP30 | |
| SCHEMBL11523017 | 0.95 | GRIA1 (0.44) | GRIA1GRIA2GRIA3HRH3USP30 | |
| SCHEMBL11524026 | 0.92 | GRIA1 (0.47) | GRIA1GRIA2GRIA3HRH3USP30 | |
| SCHEMBL11524029 | 0.92 | GRIA1 (0.47) | GRIA1GRIA2GRIA3HRH3USP30 | |
| SCHEMBL11667619 | 0.87 | GPR88 (0.35) | GRIA1GRIA2GRIA3HRH3RAB9A | |
| SCHEMBL11527151 | 0.87 | GRIA1 (0.49) | GRIA1GRIA2GRIA3HRH3USP30 | |
| SCHEMBL11527148 | 0.87 | GRIA1 (0.49) | GRIA1GRIA2GRIA3HRH3USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154697-A | Liquid crystalline hexahydroterphenyl derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1979-05-15 | — | — | US | disclosed |