Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.39 |
| ▸ | HRH2 | P25021 | 5/20 | 0.39 |
| ▸ | HRH1 | P35367 | 5/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11523258 | 1.00 | HRH3 (0.39) | HRH3HRH2HRH1GRIA1GRIA2 | |
| SCHEMBL11617271 | 0.89 | RAB9A (0.38) | HRH3ALDH1A1RAB9ACYP2C9LMNA | |
| SCHEMBL1006606 | 0.88 | ALDH1A1 (0.47) | ALDH1A1HPGDMGLLLMNAMAPK1 | |
| SCHEMBL11618956 | 0.87 | GRIA1 (0.38) | HRH3GRIA1GRIA2GRIA3ALDH1A1 | |
| SCHEMBL11526437 | 0.84 | HRH3 (0.39) | HRH3HRH2HRH1GRIA1GRIA2 | |
| SCHEMBL11526443 | 0.84 | HRH3 (0.39) | HRH3HRH2HRH1GRIA1GRIA2 | |
| SCHEMBL11524499 | 0.83 | RAB9A (0.52) | HRH3HRH2HRH1ALDH1A1HPGD | |
| SCHEMBL11524495 | 0.83 | RAB9A (0.52) | HRH3HRH2HRH1ALDH1A1HPGD | |
| SCHEMBL11523752 | 0.82 | GRIA1 (0.40) | GRIA1GRIA2GRIA3 | |
| SCHEMBL11624592 | 0.82 | GRIA1 (0.40) | HRH3GRIA1GRIA2GRIA3CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154697-A | Liquid crystalline hexahydroterphenyl derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1979-05-15 | — | — | US | disclosed |