Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HK1 | P19367 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9693886 | 0.74 | MAPT (0.49) | MCL1ALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL8610853 | 0.72 | CYP19A1 (0.51) | MCL1KDM4EMAPTKCNH2MEN1 | |
| SCHEMBL11526220 | 0.72 | MCL1 (0.39) | MCL1ALDH1A1SMN1; SMN2HK1HKDC1 | |
| SCHEMBL395103 | 0.72 | GSK3B (0.48) | MCL1ALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL2088995 | 0.71 | KCNH2 (0.45) | MCL1ALDH1A1SMN1; SMN2HK1HKDC1 | |
| SCHEMBL7001279 | 0.71 | CES2 (0.50) | MCL1ALDH1A1SMN1; SMN2HK1HKDC1 | |
| SCHEMBL2071218 | 0.71 | FEN1 (0.52) | MCL1ALDH1A1SMN1; SMN2HK1HKDC1 | |
| SCHEMBL8600853 | 0.70 | GSK3B (0.44) | ALDH1A1SMN1; SMN2KDM4EMAPTKMT2A | |
| SCHEMBL1554080 | 0.69 | CES2 (0.39) | MCL1ALDH1A1SMN1; SMN2HK1HKDC1 | |
| SCHEMBL25992037 | 0.68 | MCL1 (0.39) | MCL1ALDH1A1SMN1; SMN2HK1HKDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4165319-A | Isoindoline pigments | CIBA-GEIGY CORPORATION (US) | 1979-08-21 | — | — | US | disclosed |