Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 10/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31222770 | 0.82 | ALDH1A1 (0.42) | GSK3BALDH1A1HIF1AMAPK1TRPA1 | |
| SCHEMBL11457421 | 0.79 | JAK1 (0.47) | GSK3BALDH1A1HIF1AMAPK1TRPA1 | |
| SCHEMBL27692792 | 0.79 | CA12 (0.43) | GSK3BALDH1A1HIF1AMAPK1TRPA1 | |
| SCHEMBL31222807 | 0.79 | GSK3B (0.39) | GSK3BALDH1A1HIF1AMAPK1TRPA1 | |
| SCHEMBL25082656 | 0.76 | METAP2 (0.38) | GSK3BALDH1A1HIF1AMAPK1TRPA1 | |
| SCHEMBL25082808 | 0.76 | MAOA (0.36) | GSK3BALDH1A1HIF1AMAPK1TRPA1 | |
| SCHEMBL2284243 | 0.73 | GSK3B (0.52) | GSK3BALDH1A1HIF1AMAPK1TRPA1 | |
| SCHEMBL31318386 | 0.73 | GSK3B (0.52) | GSK3BALDH1A1HIF1AMAPK1TRPA1 | |
| SCHEMBL6238459 | 0.72 | TDP1 (0.45) | ALDH1A1MAPK1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL11219888 | 0.72 | THRB (0.57) | GSK3BALDH1A1HIF1AMAPK1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998049251-A1 | MULTIPLE RARE-EARTH METAL COMPLEXES | AKZO NOBEL N.V. (NL) | 1998-11-05 | — | — | WO | disclosed |