Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203370 | 0.84 | APEX1 (0.58) | APEX1BLMALDH1A1KMT2AALOX15 | |
| SCHEMBL9301450 | 0.84 | APEX1 (0.58) | APEX1BLMALDH1A1KMT2AALOX15 | |
| SCHEMBL9203374 | 0.84 | APEX1 (0.58) | APEX1BLMALDH1A1KMT2AALOX15 | |
| SCHEMBL12251961 | 0.77 | APEX1 (0.55) | APEX1BLMCYP2C19KMT2AL3MBTL1 | |
| SCHEMBL11618863 | 0.75 | APEX1 (0.50) | APEX1BLMCYP2C19ALDH1A1KMT2A | |
| SCHEMBL7068440 | 0.74 | KAT2B (0.43) | KAT2BLMNAALDH1A1KMT2AALOX15 | |
| SCHEMBL9793623 | 0.74 | CYP1A2 (0.41) | HIF1ACYP2D6CYP2C19KAT2BLMNA | |
| SCHEMBL15042020 | 0.74 | SMN1; SMN2 (0.45) | LMNAALDH1A1KMT2AL3MBTL1TSHR | |
| SCHEMBL11523135 | 0.73 | — | — | |
| SCHEMBL30752552 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4173569-A | Preparation of pyrrolidine and pyrrolidin-2-one derivatives | I.S.F. SPA (IT) | 1979-11-06 | — | — | US | disclosed |