Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | GSK3A | P49840 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.38 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203374 | 1.00 | APEX1 (0.58) | APEX1BLMGSK3AGSK3BELANE | |
| SCHEMBL9203370 | 1.00 | APEX1 (0.58) | APEX1BLMGSK3AGSK3BELANE | |
| SCHEMBL11523742 | 0.84 | APEX1 (0.47) | APEX1BLMKMT2AALDH1A1ALOX15 | |
| SCHEMBL21389170 | 0.83 | APEX1 (0.62) | APEX1BLMKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL21389109 | 0.83 | APEX1 (0.62) | APEX1BLMKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9301677 | 0.81 | GSK3A (0.41) | APEX1BLMGSK3AGSK3BELANE | |
| SCHEMBL10681074 | 0.81 | ALDH1A1 (0.43) | GSK3AGSK3BELANEALDH1A1PIN1 | |
| SCHEMBL10626979 | 0.80 | APEX1 (0.54) | APEX1BLMTDP1RAB9AALDH1A1 | |
| SCHEMBL563088 | 0.80 | GSK3A (0.41) | APEX1BLMGSK3AGSK3BELANE | |
| SCHEMBL563087 | 0.80 | GSK3A (0.41) | APEX1BLMGSK3AGSK3BELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104483400-B | Method for separating and measuring oxiracetam and intermediate thereof by liquid chromatography | 万全万特制药（厦门）有限公司 | 2020-07-31 | — | — | CN | claimed |
| CN-101914052-A | Oxiracetam compound and new method thereof | JIANRONG HU | 2010-12-15 | — | — | CN | claimed |
| CN-111454190-A | Method for synthesizing oxiracetam by adopting NaA type molecular membrane reactor | 中海油天津化工研究设计院有限公司 | 2020-07-28 | — | — | CN | disclosed |
| CN-102846600-B | Oxiracetam drug activity composition and preparation method thereof | CSPC PHARMACEUTICAL GROUP OUYI PHARMA CO LTD | 2015-06-17 | — | — | CN | disclosed |
| CN-102746207-B | Synthesis method of oxiracetam | XINTAI PHARMACEUTICAL SUZHOU CO LTD | 2013-12-25 | — | — | CN | disclosed |
| CN-102846600-A | Oxiracetam drug activity composition and preparation method thereof | CSPC PHARMACEUTICAL GROUP OUYI PHARMA CO LTD | 2013-01-02 | — | — | CN | disclosed |
| CN-102134212-A | Preparation method of Oxiracetam | CHONGQING SHENGHUAXI PHARMA CO | 2011-07-27 | — | — | CN | disclosed |
| CN-101914052-A | Oxiracetam compound and new method thereof | JIANRONG HU | 2010-12-15 | — | — | CN | disclosed |
| CN-1268611-C | Method of preparing 4-hydroxy pyrrolidone-2-acetamine | ZHANGJIAGANG HAOBO CHEMICALS C (CN) | 2006-08-09 | — | — | CN | disclosed |
| CN-1513836-A | Method of preparing 4-hydroxy pyrrolidone-2-acetamine | 张家港浩波化学品有限公司 | 2004-07-21 | — | — | CN | disclosed |
| US-5371237-A | Process for the production of 4-hydroxy-2-oxopyrrolidin-1-yl-acetamide | LONZA LTD. (CH) | 1994-12-06 | — | — | US | disclosed |
| US-4824861-A | Pyrrolidone derivatives and memory enhancement use thereof | ISF SOCIETA PER AZIONI (IT) | 1989-04-25 | — | — | US | disclosed |
| US-4824966-A | Process for the production of 4-hydroxy-2-oxo-pyrrolidin-1-yl acetamide | LONZA LTD. (CH) | 1989-04-25 | — | — | US | disclosed |
| US-4788300-A | Substituted butanamido acetate compounds for the preparation of pyrrolidone derivatives | I.S.F. SOCIETA PER AZIONI (IT) | 1988-11-29 | — | — | US | disclosed |
| EP-0156655-B1 | PROCESS FOR THE PREPARATION OF PYRROLIDONE DERIVATIVES | I.S.F. Socièta per Azioni (IT) | 1988-11-23 | — | — | EP | disclosed |
| EP-0207681-A2 | Pyrrolidone derivatives | ISF SOCIETA PER AZIONI (IT) | 1987-01-07 | — | — | EP | disclosed |
| US-4629797-A | Process for the preparation of pyrrolidone derivatives | I.S.F. SOCIETA PER AZIONI (IT) | 1986-12-16 | — | — | US | disclosed |
| EP-0156655-A2 | Process for the preparation of pyrrolidone derivatives | I.S.F. Socièta per Azioni (IT) | 1985-10-02 | — | — | EP | disclosed |
| US-4173569-A | Preparation of pyrrolidine and pyrrolidin-2-one derivatives | I.S.F. SPA (IT) | 1979-11-06 | — | — | US | disclosed |
| US-4118396-A | PYRROLIDIN-2-ONES, CNS AGENTS | I.S.F. S.P.A. (IT) | 1978-10-03 | — | — | US | disclosed |