Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11526561 | 0.84 | L3MBTL1 (0.51) | MAPTALDH1A1TDP1NPC1SMN1; SMN2 | |
| SCHEMBL10900628 | 0.83 | THRB (0.54) | TSHRMAPTALDH1A1TDP1NPC1 | |
| SCHEMBL11522662 | 0.80 | SMN1; SMN2 (0.54) | CYP2C19MAPTALDH1A1POLBNPC1 | |
| SCHEMBL27451062 | 0.80 | MAPT (0.51) | TSHRMAPTPTGS2ALDH1A1TDP1 | |
| SCHEMBL3771178 | 0.79 | CYP1A2 (0.53) | CYP1A2CYP3A4CYP2C19BLMPMP22 | |
| SCHEMBL28531006 | 0.78 | CYP1A2 (0.60) | CYP1A2CYP3A4CYP2C19BLMPMP22 | |
| SCHEMBL11522867 | 0.77 | MAPT (0.48) | CYP1A2CYP3A4CYP2C19MAPTALDH1A1 | |
| SCHEMBL6890414 | 0.76 | MCL1 (0.43) | CYP2C19BLMMAPTTDP1KMT2A | |
| SCHEMBL28492938 | 0.76 | CYP1A2 (0.54) | CYP1A2CYP3A4CYP2C19BLMPMP22 | |
| SCHEMBL11527659 | 0.76 | HRH3 (0.48) | CYP3A4BLMTSHRMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172944-A | Water insoluble styryl dyestuffs having hetero-aryl methylene substituent | BAYER AKTIENGESELLSCHAFT (DE) | 1979-10-30 | — | — | US | disclosed |
| US-4077962-A | WATER INSOLUBLE, GREEN-YELLOW, SYNTHETIC FIBERS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-03-07 | — | — | US | disclosed |
| US-4046771-A | GREENISH-YELLOW SHADES ON SYNTHETIC FIBERS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-06 | — | — | US | disclosed |
| US-4016191-A | WATER INSOLUBLE; LIGHTFASTNESS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-04-05 | — | — | US | disclosed |