Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14273072 | 0.87 | PTGDR2 (0.57) | L3MBTL1KDM4EPTGDR2SMN1; SMN2 | |
| SCHEMBL15296803 | 0.87 | ABCB1 (0.55) | L3MBTL1PTGDR2KMT2ALMNAMAPT | |
| SCHEMBL7860492 | 0.83 | MAPK1 (0.51) | ALDH1A1MAPK1HSD17B10KMT2ALMNA | |
| SCHEMBL8376379 | 0.82 | MEN1 (0.43) | L3MBTL1ALDH1A1KDM4EMAPK1KMT2A | |
| SCHEMBL12180298 | 0.81 | MAPT (0.51) | L3MBTL1ALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL27540093 | 0.81 | KMT2A (0.45) | L3MBTL1ALDH1A1KDM4EPTGDR2KMT2A | |
| SCHEMBL16220554 | 0.80 | MEN1 (0.59) | ALDH1A1HPGDHSD17B10KMT2ALMNA | |
| SCHEMBL9628911 | 0.79 | ALDH1A1 (0.44) | L3MBTL1ALDH1A1HPGDKDM4EMAPK1 | |
| SCHEMBL2190365 | 0.79 | ACHE (0.59) | ALDH1A1MAPK1MAPTHTTMAPK8 | |
| SCHEMBL7718767 | 0.78 | MAPT (0.59) | L3MBTL1ALDH1A1KDM4EKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4137328-A | CONGESTIVE HEART FAILURE | PFIZER INC. (US) | 1979-01-30 | — | — | US | disclosed |