Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | PDE1A | P54750 | 1/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11526231 | 0.90 | SLC6A4 (0.43) | SLC6A4SLC6A3SLC6A2NPC1RAB9A | |
| SCHEMBL10590633 | 0.90 | SLC6A4 (0.46) | SLC6A4SLC6A3SLC6A2NPC1RAB9A | |
| SCHEMBL11524015 | 0.82 | SLC6A4 (0.63) | SLC6A4SLC6A3SLC6A2NPC1RAB9A | |
| SCHEMBL10768525 | 0.79 | SLC6A4 (0.46) | SLC6A4SLC6A3SLC6A2CYP19A1 | |
| SCHEMBL10586709 | 0.77 | SLC6A3 (0.43) | SLC6A4SLC6A3SLC6A2HSD17B10CYP19A1 | |
| SCHEMBL10591071 | 0.76 | SLC6A4 (0.43) | SLC6A4SLC6A3SLC6A2CYP19A1 | |
| SCHEMBL30968977 | 0.75 | SLC6A4 (0.40) | SLC6A4SLC6A3SLC6A2CYP19A1 | |
| SCHEMBL10589716 | 0.74 | SLC6A4 (0.62) | SLC6A4SLC6A3SLC6A2HSD11B1 | |
| SCHEMBL11524868 | 0.74 | CNR2 (0.49) | SLC6A4SLC6A3SLC6A2HSD11B1 | |
| SCHEMBL6891431 | 0.72 | SLC6A3 (0.40) | SLC6A4SLC6A3SLC6A2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154697-A | Liquid crystalline hexahydroterphenyl derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1979-05-15 | — | — | US | disclosed |