Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | GBA1 | P04062 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GRM5 | P41594 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.51 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.51 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11524346 | 0.89 | KMT2A (0.55) | KMT2AMEN1RAB9ANPC1GBA1 | |
| SCHEMBL2483166 | 0.85 | KMT2A (0.72) | KMT2AMEN1RAB9ANPC1GBA1 | |
| SCHEMBL30070833 | 0.85 | KMT2A (0.72) | KMT2AMEN1RAB9ANPC1GBA1 | |
| SCHEMBL11524453 | 0.78 | CHRNB2 (0.45) | KMT2AMEN1ALDH1A1LMNAKDM4E | |
| SCHEMBL5034141 | 0.78 | RAB9A (0.72) | KMT2AMEN1RAB9ANPC1GBA1 | |
| SCHEMBL30509648 | 0.78 | RAB9A (0.72) | KMT2AMEN1RAB9ANPC1GBA1 | |
| SCHEMBL11524091 | 0.78 | KMT2A (0.72) | KMT2AMEN1RAB9ANPC1GBA1 | |
| SCHEMBL31725239 | 0.77 | RAB9A (0.78) | KMT2AMEN1RAB9ANPC1GBA1 | |
| SCHEMBL3119185 | 0.77 | RAB9A (0.78) | KMT2AMEN1RAB9ANPC1GBA1 | |
| SCHEMBL4327363 | 0.76 | KMT2A (0.74) | KMT2AMEN1RAB9ANPC1GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4164579-A | ANTI-ULCER AGENTS | RHONE-POULENC INDUSTRIES (FR) | 1979-08-14 | — | — | US | claimed |
| US-4167571-A | Thiazoline derivatives | RHONE-POULENC INDUSTRIES (FR) | 1979-09-11 | — | — | US | disclosed |
| US-4164579-A | ANTI-ULCER AGENTS | RHONE-POULENC INDUSTRIES (FR) | 1979-08-14 | — | — | US | disclosed |