Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | BAD | Q92934 | 1/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8535639 | 0.82 | MAPT (0.42) | ALDH1A1CYP1A2CYP2C19CYP3A4MAPT | |
| SCHEMBL8536480 | 0.82 | ALDH1A1 (0.38) | ALDH1A1KDM4ECYP1A2CYP2C19CYP3A4 | |
| SCHEMBL4592585 | 0.70 | CYP1A2 (0.49) | ALDH1A1KDM4ECYP1A2CYP2C19CYP3A4 | |
| SCHEMBL11451306 | 0.70 | ALDH1A1 (0.41) | ALDH1A1KDM4ECYP1A2CYP2C19CYP3A4 | |
| SCHEMBL11442064 | 0.70 | CYP1A2 (0.49) | ALDH1A1KDM4ECYP1A2CYP2C19CYP3A4 | |
| SCHEMBL27416804 | 0.69 | CES2 (0.45) | CES2CES1ALDH1A1KDM4EMAPT | |
| SCHEMBL353005 | 0.69 | ALDH1A1 (0.40) | ALDH1A1KDM4ECYP1A2CYP2C19CYP3A4 | |
| SCHEMBL11524479 | 0.67 | ALDH1A1 (0.40) | ALDH1A1KDM4ECYP1A2CYP2C19CYP3A4 | |
| SCHEMBL10524449 | 0.66 | CES2 (0.50) | CES2CES1ALDH1A1KDM4ECYP2C19 | |
| SCHEMBL227735 | 0.66 | CES2 (0.41) | CES2CES1CA1CA2BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3998875-A | PROCESS OF PREPARING 5-FLUORO-2-METHYL-1-(PARAMETHYLSULFINYLBENZYLIDENE)-INDENYL-3-ACETIC ACID | MERCK & CO., INC. (US) | 1976-12-21 | — | — | US | claimed |
| US-4167640-A | 5-Fluoro-2-methyl-ind-1-ene-3-acetic acid | MERCK & CO., INC. (US) | 1979-09-11 | — | — | US | disclosed |
| US-4123457-A | 2-Methyl-5-fluoro-indanol-3-acetic acid | MERCK & CO., INC. (US) | 1978-10-31 | — | — | US | disclosed |
| US-3998875-A | PROCESS OF PREPARING 5-FLUORO-2-METHYL-1-(PARAMETHYLSULFINYLBENZYLIDENE)-INDENYL-3-ACETIC ACID | MERCK & CO., INC. (US) | 1976-12-21 | — | — | US | disclosed |