Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.54 |
| ▸ | SYK | P43405 | 1/20 | 0.54 |
| ▸ | ACE | P12821 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 3/20 | 0.52 |
| ▸ | CTSL | P07711 | 2/20 | 0.52 |
| ▸ | CTSB | P07858 | 2/20 | 0.52 |
| ▸ | CTSK | P43235 | 2/20 | 0.52 |
| ▸ | TACR1 | P25103 | 1/20 | 0.51 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30872660 | 1.00 | MAPT (0.54) | MAPTPOLBMAPK1KLK5SYK | |
| SCHEMBL11524379 | 0.98 | MAPT (0.56) | MAPTPOLBMAPK1KLK5SYK | |
| SCHEMBL30487456 | 0.98 | MAPT (0.56) | MAPTPOLBMAPK1KLK5SYK | |
| SCHEMBL18239621 | 0.91 | KLK5 (0.52) | MAPTPOLBKLK5SYKACE | |
| SCHEMBL2480396 | 0.91 | KLK5 (0.65) | POLBKLK5ACECTSSCTSL | |
| SCHEMBL23332639 | 0.90 | KLK5 (0.59) | MAPTPOLBKLK5SYKACE | |
| SCHEMBL28582380 | 0.90 | KLK5 (0.59) | MAPTPOLBKLK5SYKACE | |
| SCHEMBL30100570 | 0.89 | CTSS (0.56) | KLK5SYKACECTSSCTSL | |
| SCHEMBL1673615 | 0.89 | KLK5 (0.56) | MAPTPOLBMAPK1KLK5SYK | |
| SCHEMBL1673614 | 0.89 | KLK5 (0.56) | MAPTPOLBMAPK1KLK5SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024075813-A1 | POLYPEPTIDE SYNTHESIS USING DIKETOPIPERAZINE COMPOUND | 学校法人中部大学 | 2024-04-11 | — | — | WO | disclosed |
| US-4144228-A | Methionine5 -enkephalin sulfoxides and sulfones | G. D. SEARLE & CO. (US) | 1979-03-13 | — | — | US | disclosed |