Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11525022 | 0.90 | TDP1 (0.49) | TDP1MAPK1CYP3A4TSHRMAPT | |
| SCHEMBL11523919 | 0.86 | TDP1 (0.50) | TDP1MAPK1CYP3A4TSHRMAPT | |
| SCHEMBL11317064 | 0.80 | TDP1 (0.55) | TDP1MAPK1CYP3A4TSHRMAPT | |
| SCHEMBL9751826 | 0.78 | TDP1 (0.56) | TDP1MAPK1CYP3A4TSHRMAPT | |
| SCHEMBL11523364 | 0.78 | TDP1 (0.52) | TDP1MAPK1CYP3A4TSHRMAPT | |
| SCHEMBL11328343 | 0.78 | MAPT (0.51) | TDP1MAPK1CYP3A4TSHRMAPT | |
| SCHEMBL11321924 | 0.75 | TDP1 (0.50) | TDP1MAPK1CYP3A4TSHRMAPT | |
| SCHEMBL8331984 | 0.75 | CYP3A4 (0.49) | TDP1MAPK1CYP3A4TSHRMAPT | |
| SCHEMBL11527037 | 0.75 | TDP1 (0.43) | TDP1MAPK1CYP3A4TSHRMAPT | |
| SCHEMBL5264717 | 0.74 | TSHR (0.51) | TDP1CYP3A4TSHRMAPTGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4136117-A | PREPARATION OF 2,6-DINITROANILINES | AMERICAN CYANAMID COMPANY (US) | 1979-01-23 | — | — | US | disclosed |