Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PHGDH | O43175 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11529508 | 0.72 | HTT (0.53) | MAPTKMT2ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL27470351 | 0.65 | RECQL (0.58) | MGLLKMT2ARECQLALDH1A1GLA | |
| SCHEMBL7295033 | 0.64 | LMNA (0.46) | LMNA | |
| SCHEMBL7295038 | 0.64 | LMNA (0.46) | LMNA | |
| SCHEMBL304820 | 0.64 | TSHR (0.50) | MGLLRECQLSMN1; SMN2ALDH1A1GLA | |
| SCHEMBL14438970 | 0.64 | RECQL (0.56) | MGLLKMT2ARECQLSMN1; SMN2ALDH1A1 | |
| SCHEMBL14426767 | 0.64 | RECQL (0.56) | MGLLKMT2ARECQLSMN1; SMN2ALDH1A1 | |
| SCHEMBL6627605 | 0.64 | RECQL (0.56) | MGLLKMT2ARECQLSMN1; SMN2ALDH1A1 | |
| SCHEMBL4678814 | 0.64 | RECQL (0.56) | MGLLKMT2ARECQLSMN1; SMN2ALDH1A1 | |
| SCHEMBL2828543 | 0.64 | RECQL (0.56) | MGLLKMT2ARECQLSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156735-A | SALIDIURETICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |
| US-4118501-A | SALIDIURETIC ACTIVITY | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |