SCHEMBL11524911

SCHEMBL11524911

CCC(C)Nc1ccc(OCCCOc2ccc(NC(C)CC)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.67
TSHR P16473 2/20 0.67
TDP1 Q9NUW8 2/20 0.67
L3MBTL1 Q9Y468 2/20 0.67
TP53 P04637 1/20 0.67
HSP90AA1 P07900 1/20 0.67
CYP3A4 P08684 1/20 0.67
THRB P10828 1/20 0.67
ALOX15 P16050 1/20 0.67
CASP1 P29466 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
HIF1A Q16665 1/20 0.67
HSD17B10 Q99714 1/20 0.67
KDM4E B2RXH2 3/20 0.47
EPHX2 P34913 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
HRH3 Q9Y5N1 1/20 0.40
CXCL12 P48061 1/20 0.40
PLA2G4B P0C869 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11529008 0.96 ALDH1A1 (0.67) ALDH1A1TSHRTDP1L3MBTL1TP53
SCHEMBL11531576 0.95 ALDH1A1 (0.64) ALDH1A1TSHRTDP1L3MBTL1TP53
SCHEMBL11533693 0.95 ALDH1A1 (0.64) ALDH1A1TSHRTDP1L3MBTL1TP53
SCHEMBL11529455 0.94 ALDH1A1 (0.69) ALDH1A1TSHRTDP1L3MBTL1TP53
SCHEMBL5624927 0.87 ALDH1A1 (0.69) ALDH1A1TSHRTDP1L3MBTL1TP53
SCHEMBL11533241 0.86 L3MBTL1 (0.47) ALDH1A1TSHRTDP1L3MBTL1TP53
SCHEMBL11531871 0.84 SLC2A1 (0.48) ALDH1A1TSHRTDP1L3MBTL1TP53
SCHEMBL11529802 0.84 MAPK1 (0.54) ALDH1A1TSHRTDP1L3MBTL1TP53
SCHEMBL11528989 0.84 EPHX2 (0.53) ALDH1A1TSHRTDP1L3MBTL1TP53
SCHEMBL11534127 0.83 NPC1 (0.44) ALDH1A1TSHRTDP1L3MBTL1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4161474-A STABILIZERS, ANTIOZONANTS FOR VULCANIZABLE DIENE RUBBERS MONSANTO COMPANY (US) 1979-07-17 US disclosed