Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | HTR7 | P34969 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | HTR2B | P41595 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14454750 | 0.98 | HTR2C (0.54) | HTR2CHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL14454751 | 0.90 | HTR2A (0.46) | HTR2CHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL14454755 | 0.86 | L3MBTL1 (0.51) | HTR2CHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL11730281 | 0.84 | HTR1A (0.54) | HTR2CHTR1AHTR2AHTR7DRD3 | |
| Hydrochloric Acid SCHEMBL8536805 | 0.83 | HTR1A (0.68) | HTR2CHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL14454756 | 0.82 | HTR1A (0.71) | HTR2CHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL11633665 | 0.81 | DRD4 (0.53) | HTR2CHTR1AHTR2AHTR7DRD3 | |
| Hydrochloric Acid SCHEMBL8536660 | 0.81 | HTR1A (0.69) | HTR2CHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL14454749 | 0.79 | MEN1 (0.50) | HTR2CHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL5583088 | 0.78 | MCHR1 (0.50) | HTR2CDRD2MCHR1HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070173498-A1 | Melanin concentrating hormone antagonist | KATO KANEYOSHI | 2007-07-26 | — | — | US | disclosed |
| US-20070173498-A1 | Melanin concentrating hormone antagonist | KATO KANEYOSHI | 2007-07-26 | — | — | US | disclosed |
| US-4148897-A | VASODILATOR, CEREBRAL BLOOD FLOW INCREASING | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070173498-A1 | Melanin concentrating hormone antagonist | MC1R, MCHR1, MCHR2 | HTR2C 195/4885HTR1A 73/4885HTR2A 158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.