SCHEMBL11525002

SCHEMBL11525002

CC(CN(CCCl)c1ccc(C=O)c(Cl)c1)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
AOC3 Q16853 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
EGFR P00533 2/20 0.34
ERBB2 P04626 2/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
BCHE P06276 1/20 0.32
ACHE P22303 1/20 0.32
MEN1 O00255 2/20 0.32
MAPT P10636 2/20 0.32
KMT2A Q03164 2/20 0.32
KDM4E B2RXH2 1/20 0.32
HPGD P15428 1/20 0.32
HTT P42858 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
SLC2A1 P11166 1/20 0.32
P2RX7 Q99572 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9730719 0.80 TDP1 (0.48) ALDH1A1L3MBTL1TDP1EGFRERBB2
SCHEMBL11639773 0.75 AOC3 (0.41) ALDH1A1AOC3EGFRERBB2NPC1
SCHEMBL7085605 0.71 SLC16A3 (0.45) ALDH1A1L3MBTL1TDP1
SCHEMBL9733725 0.70 ALDH1A1 (0.66) ALDH1A1L3MBTL1TDP1BCHEACHE
SCHEMBL10333910 0.68 ALDH1A1 (0.49) ALDH1A1L3MBTL1TDP1EGFRERBB2
SCHEMBL11525242 0.68 ALDH1A1 (0.47) ALDH1A1L3MBTL1EGFRERBB2MEN1
SCHEMBL11638889 0.67 ALDH1A1 (0.49) ALDH1A1L3MBTL1TDP1EGFRERBB2
SCHEMBL31696766 0.66 ALDH1A1 (0.41) ALDH1A1L3MBTL1TDP1EGFRERBB2
SCHEMBL11526165 0.66 ALDH1A1 (0.48) ALDH1A1L3MBTL1AOC3EGFRERBB2
SCHEMBL1002405 0.65 TDP1 (0.55) ALDH1A1L3MBTL1TDP1EGFRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4172944-A Water insoluble styryl dyestuffs having hetero-aryl methylene substituent BAYER AKTIENGESELLSCHAFT (DE) 1979-10-30 US disclosed
US-4046771-A GREENISH-YELLOW SHADES ON SYNTHETIC FIBERS BAYER AKTIENGESELLSCHAFT (DT) 1977-09-06 US disclosed
US-4016191-A WATER INSOLUBLE; LIGHTFASTNESS BAYER AKTIENGESELLSCHAFT (DT) 1977-04-05 US disclosed