Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 5/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | THPO | P40225 | 2/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31696766 | 0.83 | ALDH1A1 (0.41) | TDP1ALDH1A1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL10333910 | 0.81 | ALDH1A1 (0.49) | TDP1ALDH1A1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL11697271 | 0.81 | ALDH1A1 (0.40) | TDP1ALDH1A1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL11265833 | 0.81 | TYR (0.41) | TDP1ALDH1A1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL9733725 | 0.81 | ALDH1A1 (0.66) | TDP1ALDH1A1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL11525002 | 0.80 | ALDH1A1 (0.36) | TDP1ALDH1A1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL7085605 | 0.76 | SLC16A3 (0.45) | TDP1ALDH1A1L3MBTL1TSHRCYP1A2 | |
| SCHEMBL9513863 | 0.74 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL1002405 | 0.74 | TDP1 (0.55) | TDP1ALDH1A1L3MBTL1MAPTKDM4E | |
| SCHEMBL29848301 | 0.74 | TDP1 (0.55) | TDP1ALDH1A1L3MBTL1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091501-A | Process for preparing 2H-1-benzopyran-2-ones and polyesters containing 2H-1-benzopyran-2-one residues | EASTMAN KODAK COMPANY (US) | 1992-02-25 | — | — | US | disclosed |