Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11527904 | 0.89 | ALDH1A1 (0.42) | ALDH1A1CYP3A4HSD17B10LMNANLRP3 | |
| SCHEMBL11526100 | 0.83 | ALDH1A1 (0.34) | ALDH1A1HSD17B10CYP2C19KDM4E | |
| SCHEMBL11526836 | 0.83 | ALDH1A1 (0.38) | ALDH1A1CYP3A4HSD17B10LMNANLRP3 | |
| SCHEMBL11533876 | 0.75 | ALDH1A1 (0.46) | ALDH1A1CYP3A4LMNACYP2C19ALOX15 | |
| SCHEMBL11594239 | 0.75 | ALDH1A1 (0.33) | ALDH1A1CYP3A4 | |
| SCHEMBL11529890 | 0.71 | ALDH1A1 (0.38) | ALDH1A1HSD17B10CYP2C19KDM4E | |
| SCHEMBL11529521 | 0.68 | ALDH1A1 (0.37) | ALDH1A1CYP3A4NLRP3 | |
| SCHEMBL27596741 | 0.65 | ALDH1A1 (0.43) | ALDH1A1CYP3A4HSD17B10LMNANLRP3 | |
| SCHEMBL6064480 | 0.65 | — | — | |
| SCHEMBL132773 | 0.64 | ALDH1A1 (0.78) | ALDH1A1CYP3A4HSD17B10LMNACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4132750-A | RING OPENING POLYMERIZATION OF NORBORNENE DERIVATIVES | SHOWA DENKO K.K. (JP) | 1979-01-02 | — | — | US | disclosed |
| US-4028482-A | LOW VISCOSITY POLYALKENAMER | SHOWA DENKO KABUSHIKI KAISHA (JA) | 1977-06-07 | — | — | US | disclosed |
| US-3959234-A | CATALYSTS OF ORGANOALUMINUM COMPOUNDS AND A TUNGSTEN OR MOLYBDENUM COMPOUND, RING-OPENING | SHOWA DENKO KABUSHIKI KAISHA (JA) | 1976-05-25 | — | — | US | disclosed |