Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | WRN | Q14191 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11529890 | 0.90 | ALDH1A1 (0.38) | ALDH1A1HPGDCYP1A2CYP2C19BLM | |
| SCHEMBL11525262 | 0.83 | ALDH1A1 (0.38) | ALDH1A1CYP2C19KDM4EHSD17B10 | |
| SCHEMBL11529368 | 0.77 | NLRP3 (0.42) | ALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL11527904 | 0.72 | ALDH1A1 (0.42) | ALDH1A1HPGDCYP1A2CYP2C19KDM4E | |
| SCHEMBL11527619 | 0.70 | ALDH1A1 (0.33) | ALDH1A1HPGDCYP1A2CYP2C19BLM | |
| SCHEMBL7641621 | 0.67 | ALDH1A1 (0.52) | ALDH1A1HPGDCYP1A2CYP2C19BLM | |
| SCHEMBL11582658 | 0.66 | LMNA (0.46) | ALDH1A1HPGDCYP1A2CYP2C19KDM4E | |
| SCHEMBL3134365 | 0.65 | ALDH1A1 (0.50) | ALDH1A1GAANAAA | |
| SCHEMBL21517458 | 0.63 | ALOX15 (0.44) | ALDH1A1HPGDHIF1AKDM4EHSD17B10 | |
| SCHEMBL23706607 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4132750-A | RING OPENING POLYMERIZATION OF NORBORNENE DERIVATIVES | SHOWA DENKO K.K. (JP) | 1979-01-02 | — | — | US | disclosed |