Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 3/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11521781 | 1.00 | LMNA (0.48) | LMNADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL29019748 | 0.93 | LMNA (0.41) | LMNADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL8437006 | 0.91 | CYP3A4 (0.46) | LMNADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL8436733 | 0.86 | CYP3A4 (0.39) | LMNADNM1TSHRCYP3A4L3MBTL1 | |
| SCHEMBL28117654 | 0.83 | LMNA (0.50) | LMNADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL28561609 | 0.83 | LMNA (0.50) | LMNADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL27901572 | 0.83 | LMNA (0.50) | LMNADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL225460 | 0.82 | CYP3A4 (0.53) | LMNADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL11311699 | 0.81 | CYP3A4 (0.46) | LMNADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL11679402 | 0.80 | CYP3A4 (0.52) | LMNADNM1PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4135042-A | HALOGENATED PHOSPHATE POLYESTERS, ALIPHATIC PHOSPHITES | OLIN CORPORATION (US) | 1979-01-16 | — | — | US | disclosed |