Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6890807 | 0.83 | KMT2A (0.49) | KDM4EKMT2ATDP1 | |
| SCHEMBL3104623 | 0.71 | LMNA (0.39) | — | |
| SCHEMBL18689403 | 0.65 | MAPT (0.51) | KMT2ATDP1 | |
| SCHEMBL16378624 | 0.64 | CYP2C9 (0.37) | — | |
| SCHEMBL11520016 | 0.63 | NPSR1 (0.32) | — | |
| SCHEMBL11521157 | 0.63 | KDM4E (0.30) | KDM4EALPLALPIALPGMPI | |
| SCHEMBL11143093 | 0.63 | ALDH1A1 (0.51) | KDM4EKMT2A | |
| SCHEMBL3735701 | 0.59 | ALDH1A1 (0.49) | KDM4EKMT2A | |
| SCHEMBL16186178 | 0.57 | — | — | |
| SCHEMBL1170309 | 0.57 | FFAR1 (0.68) | KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144391-A | REPLACING AN ACETOXY GROUP BY A SULFUR NUCLEOPHILE | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |