SCHEMBL115256

SCHEMBL115256

Nc1ccc(N)c(CCS(=O)(=O)O)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.47
RECQL P46063 4/20 0.47
TSHR P16473 3/20 0.47
THRB P10828 2/20 0.47
HSD17B10 Q99714 2/20 0.47
CYP3A4 P08684 2/20 0.47
ALOX15 P16050 2/20 0.47
HPGD P15428 1/20 0.47
CASP1 P29466 1/20 0.47
CYP2D6 P10635 1/20 0.41
NT5E P21589 2/20 0.36
TDP1 Q9NUW8 4/20 0.36
PKM P14618 3/20 0.36
MAPT P10636 3/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
BLM P54132 2/20 0.36
POLB P06746 2/20 0.36
APEX1 P27695 2/20 0.36
USP2 O75604 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11283871 0.88 ALDH1A1 (0.43) ALDH1A1RECQLTSHRTHRBHSD17B10
Sulfuric Acid SCHEMBL10630546 0.86 ALDH1A1 (0.49) ALDH1A1RECQLTSHRTHRBHSD17B10
SCHEMBL10883664 0.85 TSHR (0.43) ALDH1A1RECQLTSHRTHRBHSD17B10
SCHEMBL10630574 0.83 ALDH1A1 (0.40) ALDH1A1RECQLTSHRTHRBHSD17B10
Sulfuric Acid SCHEMBL672183 0.81 ALDH1A1 (0.52) ALDH1A1RECQLTSHRTHRBHSD17B10
Sulfuric Acid SCHEMBL29836019 0.81 ALDH1A1 (0.52) ALDH1A1RECQLTSHRTHRBHSD17B10
SCHEMBL114264 0.81 ALDH1A1 (0.50) ALDH1A1RECQLTSHRTHRBHSD17B10
SCHEMBL29001917 0.81 CYP2D6 (0.38) ALDH1A1RECQLTSHRTHRBHSD17B10
Sulfuric Acid SCHEMBL28619660 0.80 ALDH1A1 (0.50) ALDH1A1RECQLTSHRTHRBHSD17B10
SCHEMBL29236431 0.80 CYP2D6 (0.41) ALDH1A1RECQLTSHRTHRBHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120057115-A1 LIQUID CRYSTAL DISPLAY DEVICE PANASONIC LIQUID CRYSTAL DISPLAY CO., LTD. 2012-03-08 US disclosed
US-5116733-A Polyvinylidene fluoride KONICA CORPORATION (JP) 1992-05-26 US disclosed
EP-0127409-B1 DISPERSION KONICA CORPORATION (JP) 1989-02-08 EP disclosed
EP-0080905-A1 Silver halide color photographic material KONICA CORPORATION (JP) 1983-06-08 EP disclosed