SCHEMBL114264

SCHEMBL114264

Nc1ccc(N)c(CS(=O)(=O)O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.50
TSHR P16473 3/20 0.50
RECQL P46063 3/20 0.50
HSD17B10 Q99714 2/20 0.50
THRB P10828 2/20 0.50
CYP3A4 P08684 2/20 0.50
ALOX15 P16050 2/20 0.50
HPGD P15428 1/20 0.50
CASP1 P29466 1/20 0.50
TDP1 Q9NUW8 4/20 0.42
NT5E P21589 2/20 0.39
PKM P14618 3/20 0.38
MAPT P10636 3/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
POLB P06746 2/20 0.38
APEX1 P27695 2/20 0.38
USP2 O75604 1/20 0.38
BLM P54132 1/20 0.38
MCL1 Q07820 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL190799 0.84 TSHR (0.46) ALDH1A1TSHRRECQLHSD17B10THRB
SCHEMBL11502375 0.81 TSHR (0.52) ALDH1A1TSHRRECQLHSD17B10THRB
SCHEMBL115256 0.81 ALDH1A1 (0.47) ALDH1A1TSHRRECQLHSD17B10THRB
SCHEMBL28287028 0.81 CYP3A4 (0.43) ALDH1A1TSHRRECQLHSD17B10THRB
Sulfuric Acid SCHEMBL6937596 0.80 ALDH1A1 (0.55) ALDH1A1TSHRRECQLHSD17B10THRB
Sulfuric Acid SCHEMBL6836529 0.80 ALDH1A1 (0.55) ALDH1A1TSHRRECQLHSD17B10THRB
Sulfuric Acid SCHEMBL6680851 0.80 ALDH1A1 (0.55) ALDH1A1TSHRRECQLHSD17B10THRB
SCHEMBL28350177 0.78 ALDH1A1 (0.38) ALDH1A1TSHRRECQLHSD17B10THRB
SCHEMBL11308302 0.78 GAA (0.51) ALDH1A1TSHRTHRBCYP3A4ALOX15
Sulfuric Acid SCHEMBL29836019 0.77 ALDH1A1 (0.52) ALDH1A1TSHRRECQLHSD17B10THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210277185-A1 COMPOSITION AND USE THEREOF JSR CORPORATION (JP) 2021-09-09 US disclosed
WO-2020121641-A1 COMPOSITION AND USE THEREFOR JSR株式会社 2020-06-18 WO disclosed
WO-2020121640-A1 METHOD FOR PRODUCING POLARIZING FILM, OPTICAL ELEMENT, AND LIQUID-CRYSTAL ELEMENT JSR株式会社 2020-06-18 WO disclosed
US-9481695-B2 Amino acid-modified siloxanes, process for preparing them and application EVONIK INDUSTRIES AG (DE) 2016-11-01 US disclosed
US-20150023900-A1 AMINO ACID-MODIFIED SILOXANES, PROCESS FOR PREPARING THEM AND APPLICATION EVONIK INDUSTRIES AG (DE) 2015-01-22 US disclosed
US-20120057115-A1 LIQUID CRYSTAL DISPLAY DEVICE PANASONIC LIQUID CRYSTAL DISPLAY CO., LTD. 2012-03-08 US disclosed
EP-0037597-B1 NOVEL CYAN-FORMING COUPLERS AND PHOTOGRAPHIC ELEMENTS CONTAINING SUCH COUPLERS AGFA-GEVAERT N.V. (BE) 1984-06-13 EP disclosed
EP-0037602-A1 Photographic elements containing novel cyan-forming colour couplers AGFA-GEVAERT N.V. (BE) 1981-10-14 EP disclosed
EP-0001852-B1 PHOTOGRAPHIC BLEACH COMPOSITIONS CONTAINING BLEACH-ACCELERATING COMPOUNDS AND THEIR USE IN A METHOD OF PROCESSING AN IMAGE-WISE EXPOSED PHOTOGRAPHIC SILVER HALIDE MATERIAL AGFA-GEVAERT N.V. (BE) 1981-05-20 EP disclosed
EP-0027284-A1 Copolymer latex and photographic silver halide materials containing such latex AGFA-GEVAERT N.V. (BE) 1981-04-22 EP disclosed
EP-0001852-A1 Photographic bleach compositions containing bleach-accelerating compounds and their use in a method of processing an image-wise exposed photographic silver halide material AGFA-GEVAERT N.V. (BE) 1979-05-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150023900-A1 AMINO ACID-MODIFIED SILOXANES, PROCESS FOR PREPARING THEM AND APPLICATION CUTA, BCAT2, PTMS ALDH1A1 1693/4885TSHR 3559/4885RECQL 4780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.