Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 2/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.37 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28224945 | 0.83 | KIF11 (0.52) | CA12CA1CA2CA9KIF11 | |
| SCHEMBL14190047 | 0.82 | CA12 (0.50) | CA12CA1CA2CA9PRKDC | |
| SCHEMBL11523983 | 0.81 | CA12 (0.51) | CA12CA1CA2CA9PRKDC | |
| SCHEMBL2182300 | 0.80 | CA12 (0.41) | CA12CA1CA2CA9ENPP1 | |
| SCHEMBL28473667 | 0.79 | KIF11 (0.68) | KIF11HDAC6HSD17B1HSD17B2 | |
| SCHEMBL13027907 | 0.79 | CA12 (0.66) | CA12CA1CA2CA9ENPP1 | |
| SCHEMBL13707355 | 0.79 | CA12 (0.47) | CA12CA1CA2CA9PRKDC | |
| SCHEMBL14705447 | 0.79 | KIF11 (0.52) | KIF11HSD17B1HSD17B2PRF1 | |
| SCHEMBL27961778 | 0.79 | KIF11 (0.52) | KIF11HSD17B1HSD17B2PRF1 | |
| SCHEMBL23212772 | 0.79 | MAPT (0.53) | CA12CA1CA2CA9HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4174405-A | MITICIDES | UNIROYAL, INC. (US) | 1979-11-13 | — | — | US | disclosed |