Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | PPARA | Q07869 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21888054 | 0.92 | HDAC8 (0.45) | KIF11HDAC8HDAC6ENPP1CA12 | |
| SCHEMBL26547938 | 0.90 | CA12 (0.48) | KIF11HDAC8HDAC6ENPP1CA12 | |
| SCHEMBL26548383 | 0.90 | CA12 (0.48) | KIF11HDAC8HDAC6ENPP1CA12 | |
| SCHEMBL26548876 | 0.89 | CA12 (0.47) | KIF11HDAC8HDAC6ENPP1CA12 | |
| SCHEMBL26548564 | 0.89 | CA12 (0.47) | KIF11HDAC8HDAC6ENPP1CA12 | |
| SCHEMBL22992967 | 0.86 | SCN5A (0.42) | KIF11HDAC8HDAC6ENPP1CA12 | |
| SCHEMBL22978409 | 0.86 | KIF11 (0.46) | KIF11HDAC8HDAC6ENPP1CA12 | |
| SCHEMBL13298650 | 0.84 | KIF11 (0.48) | KIF11HDAC8HDAC6ENPP1CA12 | |
| SCHEMBL24336313 | 0.84 | HDAC8 (0.47) | HDAC8HDAC6ENPP1CA12CA1 | |
| SCHEMBL27525626 | 0.84 | KIF11 (0.47) | KIF11ENPP1CYP2C9CYP2C19SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11866431-B2 | Bicyclic compounds | VIVACE THERAPEUTICS, INC. (US) | 2024-01-09 | — | — | US | disclosed |
| US-20230061429-A1 | BICYCLIC COMPOUNDS | VIVACE THERAPEUTICS, INC. | 2023-03-02 | — | — | US | disclosed |
| CN-108271370-A | As P2Y14Triazole derivatives as receptor antagonists | (由卫生与公众服务部部长代表的)美利坚合众国 | 2018-07-10 | — | — | CN | disclosed |
| CN-108148055-A | A kind of D- π-A types organic fluorescence materials and preparation method based on naphthalene | 陕西师范大学 | 2018-06-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11866431-B2 | Bicyclic compounds | YAP1, MYC, TEAD2 | KIF11 2038/4885HDAC8 161/4885HDAC6 276/4885 |
| US-20230061429-A1 | BICYCLIC COMPOUNDS | YAP1, MYC, TEAD2 | KIF11 2038/4885HDAC8 161/4885HDAC6 276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.