Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27739460 | 0.84 | L3MBTL1 (0.51) | NPC1MITFLMNATP53RAB9A | |
| SCHEMBL11529679 | 0.80 | POLB (0.37) | NPC1RAB9ATSHRTHRBPOLB | |
| SCHEMBL28748119 | 0.79 | KDM4E (0.56) | NPC1MITFLMNATP53RAB9A | |
| SCHEMBL31556453 | 0.78 | THRB (0.43) | SMN1; SMN2TSHRTHRBPOLBAPEX1 | |
| SCHEMBL29177490 | 0.78 | L3MBTL1 (0.51) | NPC1MITFLMNATP53RAB9A | |
| SCHEMBL31211624 | 0.77 | MAPK1 (0.55) | NPC1LMNARAB9ASMN1; SMN2HTT | |
| SCHEMBL3821123 | 0.77 | MAPK1 (0.55) | NPC1LMNARAB9ASMN1; SMN2HTT | |
| SCHEMBL9561657 | 0.76 | THRB (0.47) | TP53TSHRTHRBPOLBAPEX1 | |
| SCHEMBL11529095 | 0.75 | THRB (0.38) | SMN1; SMN2TSHRTHRBPOLBAPEX1 | |
| SCHEMBL210721 | 0.75 | SMN1; SMN2 (0.60) | NPC1LMNARAB9ASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159202-A | PHOTOCOPYING | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-06-26 | — | — | US | disclosed |