Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL572409 | 0.88 | MAPT (0.61) | MAPTTDP1L3MBTL1ALDH1A1GAA | |
| SCHEMBL11432496 | 0.86 | MAPT (0.59) | MAPTTDP1L3MBTL1ALDH1A1GAA | |
| SCHEMBL6901942 | 0.86 | MAPT (0.67) | MAPTTDP1L3MBTL1ALDH1A1GAA | |
| SCHEMBL11526837 | 0.83 | MAPT (0.54) | MAPTTDP1L3MBTL1ALDH1A1GAA | |
| SCHEMBL11514511 | 0.80 | MAPT (0.45) | MAPTTDP1L3MBTL1ALDH1A1GAA | |
| SCHEMBL9799926 | 0.80 | ALDH1A1 (0.49) | MAPTTDP1L3MBTL1ALDH1A1GAA | |
| SCHEMBL11869694 | 0.78 | MAPT (0.59) | MAPTTDP1L3MBTL1ALDH1A1GAA | |
| SCHEMBL11440633 | 0.77 | MAPT (0.58) | MAPTTDP1L3MBTL1ALDH1A1GAA | |
| SCHEMBL11522596 | 0.77 | MAPT (0.65) | MAPTTDP1L3MBTL1ALDH1A1GAA | |
| SCHEMBL7558393 | 0.75 | HCAR3 (0.42) | MAPTTDP1L3MBTL1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4165231-A | 2,6-Dinitroaniline herbicides | AMERICAN CYANAMID COMPANY (US) | 1979-08-21 | — | — | US | claimed |
| US-4101582-A | 2,6-Dinitroaniline herbicides | AMERICAN CYANAMID COMPANY (US) | 1978-07-18 | — | — | US | claimed |