Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAD52 | P43351 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | EZH2 | Q15910 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11529859 | 0.87 | GAA (0.49) | GAAKMT2AALOX15ALDH1A1LMNA | |
| SCHEMBL315320 | 0.85 | GAA (0.50) | GAAKMT2AALOX15ALDH1A1LMNA | |
| SCHEMBL11289576 | 0.85 | GAA (0.50) | GAAKMT2AALOX15ALDH1A1LMNA | |
| SCHEMBL11523500 | 0.85 | GAA (0.50) | GAAKMT2AALOX15ALDH1A1LMNA | |
| SCHEMBL20641825 | 0.81 | GAA (0.47) | GAAKMT2AALOX15ALDH1A1LMNA | |
| SCHEMBL11528520 | 0.79 | TSHR (0.34) | GAAKMT2ALMNAKDM1ATSHR | |
| SCHEMBL314123 | 0.73 | GAA (0.38) | GAALMNAKDM4E | |
| SCHEMBL6662214 | 0.73 | GAA (0.42) | GAAKMT2AALOX15ALDH1A1LMNA | |
| SCHEMBL8211292 | 0.72 | GAA (0.37) | GAALMNAKDM4E | |
| SCHEMBL11525071 | 0.72 | GAA (0.37) | GAALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177186-A | 4-SILOXY-DERIVATIVES OF STERICALLY HINDERED PIPERIDINES | CIBA-GEIGY CORPORATION (US) | 1979-12-04 | — | — | US | disclosed |