Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3864995 | 0.82 | MEN1 (0.46) | MEN1PABPC1KMT2APTPN1GAA | |
| SCHEMBL11166675 | 0.80 | MEN1 (0.37) | MEN1PABPC1KMT2AGAAMAPT | |
| SCHEMBL8918996 | 0.77 | TDP1 (0.42) | PTPN1GAAMAPTALDH1A1TDP1 | |
| SCHEMBL8582753 | 0.75 | PTPN1 (0.40) | MEN1KMT2APTPN1MAPTALDH1A1 | |
| SCHEMBL4495007 | 0.73 | PTPN1 (0.41) | MEN1PABPC1KMT2APTPN1GAA | |
| Bicarbonate SCHEMBL8582695 | 0.71 | PTPN1 (0.43) | MEN1KMT2APTPN1ALDH1A1TDP1 | |
| SCHEMBL5490268 | 0.70 | HTR1A (0.36) | GAAALDH1A1 | |
| SCHEMBL28431237 | 0.70 | HTT (0.44) | MEN1PABPC1KMT2APTPN1MAPT | |
| SCHEMBL5596024 | 0.70 | TDP1 (0.36) | PTPN1ALDH1A1TDP1 | |
| SCHEMBL583883 | 0.70 | HSPA5 (0.41) | GAAMAPTALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150206-A | SYNERGISTIC CATALYSTS | S.A. PRB (BE) | 1979-04-17 | — | — | US | disclosed |