Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GALK1 | P51570 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4495007 | 0.89 | PTPN1 (0.41) | MEN1KMT2APABPC1PTPN1TDP1 | |
| SCHEMBL28431237 | 0.86 | HTT (0.44) | MEN1KMT2APABPC1PTPN1TDP1 | |
| SCHEMBL17374923 | 0.84 | PTPN1 (0.48) | MEN1KMT2APABPC1PTPN1TDP1 | |
| SCHEMBL11525971 | 0.82 | MEN1 (0.42) | MEN1KMT2APABPC1PTPN1TDP1 | |
| SCHEMBL8966732 | 0.82 | PTPN1 (0.44) | MEN1KMT2APABPC1PTPN1TDP1 | |
| SCHEMBL11701103 | 0.82 | MEN1 (0.49) | MEN1KMT2APABPC1PTPN1MAPT | |
| SCHEMBL7125808 | 0.80 | MEN1 (0.37) | MEN1KMT2APABPC1PTPN1TDP1 | |
| SCHEMBL8998341 | 0.79 | SMN1; SMN2 (0.47) | MEN1KMT2APABPC1PTPN1MAPT | |
| SCHEMBL8950915 | 0.77 | AKR1B1 (0.50) | MEN1KMT2APABPC1PTPN1TDP1 | |
| SCHEMBL11788588 | 0.77 | MEN1 (0.45) | MEN1KMT2APABPC1PTPN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1915379-B1 | OLANZAPINE ANALOGS AND METHODS OF USE THEREOF | HYPNION INC (US) | 2009-11-11 | — | — | EP | disclosed |