Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.48 |
| ▸ | PLK1 | P53350 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | PLEC | Q15149 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11526013 | 0.84 | METAP2 (0.49) | METAP2PLK1ALDH1A1KDM4EHPGD | |
| SCHEMBL28912518 | 0.84 | KDM6B (0.57) | PLK1ALDH1A1KDM4EHPGDHCAR3 | |
| SCHEMBL2534273 | 0.82 | PLK1 (0.49) | PLK1ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL17938290 | 0.81 | ALDH1A1 (0.63) | PLK1ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL5386530 | 0.81 | PLK1 (0.58) | PLK1ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL18677636 | 0.79 | ALDH1A1 (0.53) | PLK1ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL13822547 | 0.79 | PTPRC (0.50) | PLK1ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL20563146 | 0.79 | APEX1 (0.50) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL3040698 | 0.79 | KDM4E (0.67) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13921285 | 0.79 | CLCN2 (0.49) | METAP2PLK1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4132774-A | SUNSCREEN AGENTS | GAF CORPORATION (US) | 1979-01-02 | — | — | US | disclosed |