Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.46 |
| ▸ | TYR | P14679 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.44 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6130125 | 0.93 | ALOX15 (0.45) | ALDH1A1ALOX15CYP2C9TYRHSD17B10 | |
| SCHEMBL10630193 | 0.85 | ALDH1A1 (0.48) | ALDH1A1ALOX15CYP2C9TYRHSD17B10 | |
| SCHEMBL2862111 | 0.85 | ALDH1A1 (0.54) | ALDH1A1ALOX15CYP2C9TYRHSD17B10 | |
| SCHEMBL4982793 | 0.81 | CYP2C9 (0.68) | ALDH1A1ALOX15CYP2C9TYRHSD17B10 | |
| SCHEMBL20132974 | 0.81 | ALDH1A1 (0.46) | ALDH1A1ALOX15CYP2C9TYRHSD17B10 | |
| SCHEMBL10899771 | 0.81 | ALDH1A1 (0.46) | ALDH1A1ALOX15CYP2C9TYRHSD17B10 | |
| SCHEMBL23387403 | 0.79 | ALOX15 (0.45) | ALDH1A1ALOX15CYP2C9TYRHSD17B10 | |
| Hydrogen Sulfide SCHEMBL11348298 | 0.79 | CYP2C9 (0.65) | ALDH1A1ALOX15CYP2C9TYRHSD17B10 | |
| SCHEMBL8415616 | 0.77 | ALOX15 (0.62) | ALDH1A1ALOX15CYP2C9TYRHSD17B10 | |
| SCHEMBL12733097 | 0.77 | ALOX15 (0.43) | ALDH1A1ALOX15CYP2C9TYRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4158027-A | BIPHENOL DERIVATIVES USED AS POLYMERIZATION INHIBITORS | ICI AMERICAS INC. (US) | 1979-06-12 | — | — | US | disclosed |
| US-4112019-A | BISPHENOL POLYMERIZATION INHIBITOR | ICI AMERICAS INC. (US) | 1978-09-05 | — | — | US | disclosed |
| US-4049731-A | VINYL MONOMERS, BIPHENOL DERIVATIVE AS POLYMERIZATION INHIBITOR | ICI UNITED STATES INC. (US) | 1977-09-20 | — | — | US | disclosed |