Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11530129 | 0.83 | LMNA (0.49) | LMNATSHRF2TDP1CYP1A2 | |
| SCHEMBL11525638 | 0.81 | KMT2A (0.52) | LMNATSHRF2TDP1ALDH1A1 | |
| SCHEMBL1730081 | 0.81 | LMNA (0.53) | LMNATSHRF2TDP1CYP1A2 | |
| SCHEMBL11532454 | 0.80 | CES2 (0.46) | LMNATSHRTDP1ALDH1A1MAPK1 | |
| SCHEMBL11528325 | 0.80 | CES2 (0.46) | LMNATSHRTDP1ALDH1A1MAPK1 | |
| SCHEMBL11530412 | 0.80 | CES2 (0.46) | LMNATSHRTDP1ALDH1A1MAPK1 | |
| SCHEMBL4050408 | 0.79 | LMNA (0.52) | LMNATSHRF2TDP1CYP1A2 | |
| Hydrochloric Acid SCHEMBL27431202 | 0.79 | LMNA (0.52) | LMNATSHRF2TDP1CYP1A2 | |
| SCHEMBL11526120 | 0.79 | ATM (0.56) | TDP1ALDH1A1KCNH2KMT2AMAPK1 | |
| SCHEMBL10196943 | 0.79 | LMNA (0.44) | LMNATSHRF2TDP1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160077-A | Process of crosslinking unsaturated hydrocarbon polymers employing novel carbamates | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-07-03 | — | — | US | disclosed |