SCHEMBL11526360

SCHEMBL11526360

Fc1ccc(N2CCN(c3ccc(F)c(Cl)c3)C2C(Cl)(Cl)Cl)cc1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KAT2B Q92831 2/20 0.41
PIN1 Q13526 1/20 0.41
KMT2A Q03164 3/20 0.40
MEN1 O00255 2/20 0.40
GAA P10253 2/20 0.40
RAD51 Q06609 1/20 0.39
PRKCZ Q05513 1/20 0.39
DRD2 P14416 2/20 0.38
DRD3 P35462 2/20 0.38
ALDH1A1 P00352 1/20 0.36
HSP90AA1 P07900 1/20 0.36
PHOSPHO1 Q8TCT1 1/20 0.36
ABCG2 Q9UNQ0 1/20 0.36
KCNH2 Q12809 1/20 0.36
ADAMTS5 Q9UNA0 2/20 0.35
CYP1A2 P05177 2/20 0.35
BRD9 Q9H8M2 1/20 0.35
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35
CYP2C9 P11712 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1010080 0.80 HTR3E (0.39) KMT2AMEN1DRD2MAPT
SCHEMBL1011384 0.78 MAPT (0.38) ALDH1A1POLBMAPTHPGD
SCHEMBL395284 0.77 HTR2A (0.48) ALDH1A1CYP1A2MAPTCYP2C9ALOX12
SCHEMBL1012948 0.76 ADRB1 (0.44) ALDH1A1ADAMTS5CYP1A2POLBMAPT
SCHEMBL11524094 0.76 HTR2A (0.43) ALDH1A1CYP1A2MAPTCYP2C9ALOX12
SCHEMBL1010081 0.74 ADRB1 (0.43) KMT2AMEN1GAAALDH1A1MAPT
SCHEMBL1010053 0.74 DRD4 (0.40) KMT2ADRD2ALDH1A1MAPT
SCHEMBL11527859 0.72 MAPT (0.42) KMT2AMEN1ALDH1A1POLBMAPT
SCHEMBL11529526 0.72 HTR2A (0.44) KMT2AMEN1GAAALDH1A1CYP1A2
SCHEMBL23843625 0.71 ABCG2 (0.48) KAT2BPIN1KMT2AMEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4161528-A INSECTICIDES; MITICIDES CELAMERCK GMBH & CO. KG. (DE) 1979-07-17 US disclosed