SCHEMBL11526375

SCHEMBL11526375

CCCCCCCc1[nH]cnc1N(C)C(=N)NC(N)=O

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
XDH P47989 4/20 0.36
SPHK1 Q9NYA1 7/20 0.32
SPHK2 Q9NRA0 2/20 0.32
ALDH1A1 P00352 1/20 0.32
ATM Q13315 1/20 0.32
EPHX1 P07099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11526215 1.00 XDH (0.36) XDHSPHK1SPHK2ALDH1A1ATM
SCHEMBL11523762 1.00 XDH (0.36) XDHSPHK1SPHK2ALDH1A1ATM
SCHEMBL11527328 0.99 XDH (0.37) XDHSPHK1SPHK2ALDH1A1ATM
SCHEMBL11526158 0.95 XDH (0.38) XDH
SCHEMBL11530603 0.92 XDH (0.32) XDHALDH1A1
SCHEMBL11522484 0.85 LMNA (0.31) XDHALDH1A1
SCHEMBL11527248 0.76 GABRR1 (0.34) ALDH1A1
Hydrochloric Acid SCHEMBL11522121 0.75 GABRR1 (0.33) ALDH1A1
SCHEMBL11526213 0.74 XDH (0.36) XDHSPHK1SPHK2EPHX1
SCHEMBL11523757 0.74 XDH (0.36) XDHSPHK1SPHK2EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4166860-A TREATMENT OF ACHLORHYDRIA AND DYSMENORRHEA WILLIAM H. RORER, INC. (US) 1979-09-04 US disclosed