Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11531493 | 0.94 | APP (0.45) | TDP1EPHX2ALDH1A1LMNACYP3A4 | |
| SCHEMBL11528528 | 0.94 | APP (0.45) | TDP1EPHX2ALDH1A1LMNACYP3A4 | |
| SCHEMBL11529872 | 0.94 | TDP1 (0.48) | TDP1EPHX2ALDH1A1LMNACYP3A4 | |
| SCHEMBL14424036 | 0.92 | NPC1 (0.51) | LMNACYP3A4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14424035 | 0.89 | NPC1 (0.57) | TSHRL3MBTL1NPC1RAB9AGAA | |
| SCHEMBL14424034 | 0.88 | CXCL12 (0.50) | EPHX2ALDH1A1NPC1RAB9AGAA | |
| SCHEMBL21600820 | 0.86 | ACACB (0.43) | TDP1EPHX2ALDH1A1LMNACYP3A4 | |
| SCHEMBL11527117 | 0.84 | EPHX2 (0.44) | TDP1EPHX2ALDH1A1CYP3A4THRB | |
| SCHEMBL10037101 | 0.83 | NQO1 (0.58) | TDP1ALDH1A1LMNATSHRL3MBTL1 | |
| SCHEMBL11524911 | 0.82 | ALDH1A1 (0.67) | TDP1EPHX2ALDH1A1CYP3A4THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161474-A | STABILIZERS, ANTIOZONANTS FOR VULCANIZABLE DIENE RUBBERS | MONSANTO COMPANY (US) | 1979-07-17 | — | — | US | disclosed |