Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LONP1 | P36776 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11529156 | 0.92 | RAB9A (0.45) | KDM4ELONP1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11529880 | 0.86 | NPC1 (0.47) | KDM4ERAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL11530756 | 0.85 | NPC1 (0.43) | KDM4ERAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL11529222 | 0.82 | NPC1 (0.44) | KDM4ERAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL24998246 | 0.80 | KDM4E (0.52) | KDM4ELONP1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11529446 | 0.80 | NPC1 (0.49) | KDM4ERAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL11529414 | 0.79 | SMN1; SMN2 (0.48) | KDM4ERAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL3400596 | 0.77 | NPC1 (0.47) | KDM4ERAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL11527512 | 0.77 | RAB9A (0.50) | KDM4ERAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL20909550 | 0.77 | KDM4E (0.50) | KDM4ELONP1RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144339-A | TREATMENT OF BILHARZIASIS | RHONE-POULENC INDUSTRIES (FR) | 1979-03-13 | — | — | US | disclosed |
| US-4138487-A | NEMATOCIDES | RHONE-POULENC INDUSTRIES (FR) | 1979-02-06 | — | — | US | disclosed |
| US-4110450-A | BILHARZIASIS | RHONE-POULENC INDUSTRIES (FR) | 1978-08-29 | — | — | US | disclosed |