Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | FEN1 | P39748 | 12/20 | 0.45 |
| ▸ | ERCC5 | P28715 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL115026 | 0.85 | GAA (0.42) | KMT2AFEN1ERCC5GAAKCNH2 | |
| SCHEMBL116013 | 0.85 | GAA (0.42) | KMT2AFEN1ERCC5GAAKCNH2 | |
| SCHEMBL114983 | 0.85 | GAA (0.42) | KMT2AFEN1ERCC5GAAKCNH2 | |
| SCHEMBL115090 | 0.84 | EGLN1 (0.45) | KMT2AFEN1ERCC5GAAKCNH2 | |
| SCHEMBL113750 | 0.80 | KDM4E (0.43) | KMT2AFEN1ERCC5GAAKDM4E | |
| SCHEMBL115107 | 0.78 | KDM4E (0.45) | KMT2AFEN1ERCC5GAAKDM4E | |
| SCHEMBL115126 | 0.78 | PDE4B (0.38) | GAAKCNH2KDM4ERCE1PDE4B | |
| SCHEMBL115127 | 0.75 | PDE4B (0.38) | KMT2AGAAKDM4ERCE1PDE4B | |
| SCHEMBL113740 | 0.73 | KDM4E (0.42) | GAAKDM4ERCE1SMN1; SMN2 | |
| SCHEMBL113779 | 0.73 | HEXA (0.40) | KMT2AGAAKDM4ERCE1PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058893-A1 | HERBICIDALLY ACTIVE KETOSULTAMS AND DIKETOPYRIDINES | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058893-A1 | HERBICIDALLY ACTIVE KETOSULTAMS AND DIKETOPYRIDINES | KHK, KCNA1, KCNA2 | KMT2A 175/4885FEN1 3630/4885ERCC5 4625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.