Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2127610 | 0.84 | KMT2A (0.50) | GAALMNATDP1MEN1KMT2A | |
| SCHEMBL4791444 | 0.83 | TSHR (0.50) | GAALMNATDP1MEN1KMT2A | |
| SCHEMBL8838326 | 0.81 | KDM4E (0.49) | GAALMNATDP1MEN1KMT2A | |
| SCHEMBL377390 | 0.78 | SLC22A6 (0.55) | GAALMNATDP1MEN1KMT2A | |
| SCHEMBL19718941 | 0.78 | MAPT (0.51) | GAALMNANPC1L3MBTL1MEN1 | |
| SCHEMBL11528338 | 0.78 | NPC1 (0.49) | GAALMNATDP1NPC1L3MBTL1 | |
| SCHEMBL11525514 | 0.78 | L3MBTL1 (0.65) | GAALMNATDP1NPC1L3MBTL1 | |
| SCHEMBL28945284 | 0.77 | MEN1 (0.53) | GAALMNATDP1MEN1KMT2A | |
| SCHEMBL6495895 | 0.76 | BCHE (0.54) | GAALMNAMEN1KMT2ASLC22A6 | |
| SCHEMBL1645317 | 0.76 | TUBB4A (0.55) | GAALMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4163759-A | Process for preparing aromatic hydroxyaldehydes | HAARMANN & REIMER GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-08-07 | — | — | US | disclosed |