Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 11/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 3/20 | 0.36 |
| ▸ | QPCT | Q16769 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11527422 | 1.00 | GRIN2D (0.39) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL11527427 | 0.87 | HRH4 (0.40) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL11192767 | 0.84 | HRH4 (0.46) | HRH4BCHEACHEHRH2QPCT | |
| SCHEMBL7753798 | 0.83 | HRH4 (0.45) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL7753802 | 0.83 | HRH4 (0.45) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL11527452 | 0.83 | HRH4 (0.47) | HRH4BCHEACHE | |
| SCHEMBL11527451 | 0.83 | HRH4 (0.47) | HRH4BCHEACHE | |
| SCHEMBL11511499 | 0.81 | HRH4 (0.35) | HRH4BCHEACHEHRH2QPCT | |
| SCHEMBL11511501 | 0.81 | HRH4 (0.35) | HRH4BCHEACHEHRH2QPCT | |
| SCHEMBL10839148 | 0.78 | HRH4 (0.39) | HRH4BCHEACHEHRH2QPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4171325-A | Chemical process | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-10-16 | — | — | US | disclosed |