SCHEMBL11527451

SCHEMBL11527451

CCN/C(=N/CCS)NC#N

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 1/20 0.47
BCHE P06276 1/20 0.35
ACHE P22303 1/20 0.35
MCL1 Q07820 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11527452 1.00 HRH4 (0.47) HRH4BCHEACHEMCL1
SCHEMBL11527422 0.83 GRIN2D (0.39) HRH4BCHEACHE
SCHEMBL11527425 0.83 GRIN2D (0.39) HRH4BCHEACHE
SCHEMBL11359774 0.82 HRH4 (0.34) HRH4BCHEACHE
SCHEMBL11359777 0.82 HRH4 (0.34) HRH4BCHEACHE
SCHEMBL11215888 0.81 BCHE (0.32) HRH4BCHEACHE
SCHEMBL9809754 0.81 BCHE (0.32) HRH4BCHEACHE
SCHEMBL9809757 0.81 BCHE (0.32) HRH4BCHEACHE
SCHEMBL11509990 0.81 BCHE (0.33) HRH4BCHEACHE
SCHEMBL11509991 0.81 BCHE (0.33) HRH4BCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4171325-A Chemical process SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1979-10-16 US disclosed