Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | RORA | P35398 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11534871 | 0.88 | KDM4E (0.60) | KMT2AKDM4ERAD52TDP1CYP1A2 | |
| SCHEMBL18405584 | 0.81 | CNR2 (0.47) | JAK2JAK1TYK2JAK3RORA | |
| SCHEMBL9886621 | 0.79 | KDM4E (0.51) | KMT2AKDM4ECYP1A2SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL11530947 | 0.78 | KDM4E (0.50) | KMT2AKDM4ECYP1A2SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL11530944 | 0.76 | MAPT (0.49) | KMT2AKDM4ECYP1A2SMN1; SMN2LMNA | |
| SCHEMBL11370097 | 0.76 | KMT2A (0.55) | KMT2AKDM4ERAD52TDP1CHRNB2 | |
| SCHEMBL11364589 | 0.76 | KMT2A (0.51) | KMT2AKDM4ERAD52TDP1CHRNB2 | |
| SCHEMBL11535686 | 0.76 | SMN1; SMN2 (0.46) | KDM4ESMN1; SMN2LMNATSHR | |
| Hydrochloric Acid SCHEMBL11412862 | 0.75 | KMT2A (0.50) | KMT2AKDM4ERAD52TDP1CHRNB2 | |
| Hydrochloric Acid SCHEMBL11380098 | 0.75 | KMT2A (0.54) | KMT2AKDM4ERAD52TDP1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4142886-A | Substituted benzimidazole compounds and use as herbicides | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1979-03-06 | — | — | US | disclosed |