Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | RAD52 | P43351 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11527429 | 0.88 | KMT2A (0.48) | KDM4ERAD52TDP1KMT2ACYP1A2 | |
| SCHEMBL10022427 | 0.82 | BRPF1 (0.49) | KDM4ERAD52TDP1KMT2ACYP1A2 | |
| SCHEMBL18405585 | 0.80 | CNR2 (0.44) | KDM4ERAD52TDP1NLRP3 | |
| SCHEMBL10989096 | 0.80 | KDM4E (0.68) | KDM4ERAD52TDP1KMT2ACYP1A2 | |
| SCHEMBL9886621 | 0.78 | KDM4E (0.51) | KDM4EKMT2ACYP1A2LMNASMN1; SMN2 | |
| SCHEMBL11535686 | 0.78 | SMN1; SMN2 (0.46) | KDM4ELMNASMN1; SMN2RAB9ATSHR | |
| Hydrochloric Acid SCHEMBL11530947 | 0.77 | KDM4E (0.50) | KDM4EKMT2ACYP1A2LMNASMN1; SMN2 | |
| SCHEMBL26790214 | 0.77 | KDM4E (0.64) | KDM4ERAD52TDP1KMT2ACYP1A2 | |
| SCHEMBL10641373 | 0.77 | KDM4E (0.64) | KDM4ERAD52TDP1KMT2ACYP1A2 | |
| SCHEMBL14369083 | 0.77 | KDM4E (0.64) | KDM4ERAD52TDP1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4142886-A | Substituted benzimidazole compounds and use as herbicides | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1979-03-06 | — | — | US | disclosed |