Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11527665 | 1.00 | LMNA (0.55) | LMNAMAPTNPC1RAB9APOLB | |
| SCHEMBL11527596 | 0.92 | MAPT (0.48) | LMNAMAPTNPC1RAB9APOLB | |
| SCHEMBL11527601 | 0.92 | MAPT (0.48) | LMNAMAPTNPC1RAB9APOLB | |
| SCHEMBL11526422 | 0.90 | NPC1 (0.46) | LMNAMAPTNPC1RAB9APOLB | |
| SCHEMBL11526427 | 0.90 | NPC1 (0.46) | LMNAMAPTNPC1RAB9APOLB | |
| SCHEMBL11530704 | 0.89 | CNR1 (0.48) | LMNAMAPTNPC1RAB9ATDP1 | |
| SCHEMBL11530698 | 0.89 | CNR1 (0.48) | LMNAMAPTNPC1RAB9ATDP1 | |
| SCHEMBL11523825 | 0.88 | RAB9A (0.51) | LMNAMAPTNPC1RAB9APOLB | |
| SCHEMBL11523821 | 0.88 | RAB9A (0.51) | LMNAMAPTNPC1RAB9APOLB | |
| SCHEMBL11528376 | 0.88 | CNR1 (0.47) | LMNAMAPTNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4137227-A | BACTERICIDES | STERLING DRUG INC. (US) | 1979-01-30 | — | — | US | disclosed |