Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1152778 | 1.00 | CTSS (0.49) | CTSSSYKMEN1KMT2AITGB3 | |
| SCHEMBL1153755 | 1.00 | CTSS (0.49) | CTSSSYKMEN1KMT2AITGB3 | |
| SCHEMBL28525877 | 0.89 | MEN1 (0.53) | CTSSSYKMEN1KMT2AITGB3 | |
| SCHEMBL16970654 | 0.89 | MEN1 (0.53) | CTSSSYKMEN1KMT2AITGB3 | |
| SCHEMBL28290296 | 0.86 | CTSS (0.53) | CTSSSYKMEN1KMT2AITGB3 | |
| SCHEMBL1198965 | 0.86 | CTSS (0.53) | CTSSSYKMEN1KMT2AITGB3 | |
| SCHEMBL28290297 | 0.86 | CTSS (0.53) | CTSSSYKMEN1KMT2AITGB3 | |
| SCHEMBL3826896 | 0.86 | CTSS (0.41) | CTSSSYKMEN1KMT2AITGB3 | |
| SCHEMBL345955 | 0.85 | CTSS (0.52) | CTSSSYKMEN1KMT2AITGB3 | |
| SCHEMBL345121 | 0.84 | CTSS (0.51) | CTSSSYKMEN1KMT2AITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110039933-A1 | S1P-1 RECEPTOR AGONISTS | PRAECIS PHARMACEUTICALS INCORPORATION (US) | 2011-02-17 | — | — | US | disclosed |
| EP-2054377-A1 | CHEMICAL COMPOUNDS | Praecis Pharmaceuticals Incorporated (US) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008024196-A1 | CHEMICAL COMPOUNDS | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 2008-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110039933-A1 | S1P-1 RECEPTOR AGONISTS | S1PR1, S1PR5, S1PR2 | CTSS 3035/4885SYK 957/4885MEN1 1800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.