Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1153755 | 0.86 | CTSS (0.49) | CTSSSYKMEN1KMT2ACTSL | |
| SCHEMBL1152783 | 0.86 | CTSS (0.49) | CTSSSYKMEN1KMT2ACTSL | |
| SCHEMBL1152778 | 0.86 | CTSS (0.49) | CTSSSYKMEN1KMT2ACTSL | |
| SCHEMBL5048223 | 0.80 | PPARA (0.44) | CTSSSYKMEN1KMT2ACTSL | |
| SCHEMBL3826892 | 0.79 | SYK (0.43) | CTSSSYKMEN1KMT2ACTSL | |
| SCHEMBL28525877 | 0.76 | MEN1 (0.53) | CTSSSYKMEN1KMT2ACTSL | |
| SCHEMBL16970654 | 0.76 | MEN1 (0.53) | CTSSSYKMEN1KMT2ACTSL | |
| SCHEMBL5049224 | 0.76 | SMN1; SMN2 (0.38) | CTSSSYKMEN1KMT2ACTSL | |
| SCHEMBL5049223 | 0.76 | HTT (0.41) | CTSSSYKMEN1KMT2ACTSL | |
| SCHEMBL7679208 | 0.74 | SYK (0.47) | CTSSSYKMEN1KMT2ACTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1625153-B1 | ACYLATED LYSOBACTIN-TYPE NONADEPSIPEPTIDES | AICURIS GMBH & CO KG (DE) | 2009-08-26 | — | — | EP | disclosed |