Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 7/20 | 0.48 |
| ▸ | GSK3A | P49840 | 2/20 | 0.48 |
| ▸ | LIG1 | P18858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | STK10 | O94804 | 2/20 | 0.42 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890003 | 0.80 | MYC (0.49) | GSK3BGSK3ALIG1ALDH1A1ALOX15 | |
| Phthalic Acid SCHEMBL28249734 | 0.76 | GSK3B (0.65) | GSK3BLIG1ALDH1A1ALOX15MYC | |
| Phthalic Acid SCHEMBL28572075 | 0.74 | GSK3B (0.62) | GSK3BLIG1ALDH1A1ALOX15MYC | |
| SCHEMBL187281 | 0.72 | GSK3B (0.53) | GSK3BSTK10SLKCHEK1AURKA | |
| SCHEMBL28462022 | 0.72 | GSK3B (0.47) | GSK3BGSK3ALIG1ALDH1A1MYC | |
| SCHEMBL10349769 | 0.71 | ALDH1A1 (0.54) | GSK3BLIG1ALDH1A1ALOX15MYC | |
| SCHEMBL30028907 | 0.71 | ALDH1A1 (0.72) | ALDH1A1ALOX15MYCL3MBTL1LMNA | |
| SCHEMBL36145 | 0.71 | ALDH1A1 (0.72) | ALDH1A1ALOX15MYCL3MBTL1LMNA | |
| Ammonia Solution, Strong SCHEMBL27929164 | 0.71 | GSK3B (0.52) | GSK3BSTK10SLKCHEK1AURKA | |
| Hydrochloric Acid SCHEMBL7579852 | 0.69 | ALDH1A1 (0.68) | ALDH1A1ALOX15MYCL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144131-A | COUPLING, REACTION OF NUCLEOPHILIC AND ELECTROPHILIC GROUPS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1979-03-13 | — | — | US | disclosed |