Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | VDR | P11473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11529392 | 0.85 | ALDH1A1 (0.39) | ALDH1A1GLATP53TSHRHIF1A | |
| SCHEMBL4891492 | 0.82 | ALDH1A1 (0.49) | ALDH1A1GLATP53TSHRHIF1A | |
| SCHEMBL4891430 | 0.71 | ALDH1A1 (0.55) | ALDH1A1GLATP53TSHRHIF1A | |
| SCHEMBL4891437 | 0.71 | ALDH1A1 (0.55) | ALDH1A1GLATP53TSHRHIF1A | |
| SCHEMBL4900583 | 0.71 | ALDH1A1 (0.55) | ALDH1A1GLATP53TSHRHIF1A | |
| SCHEMBL4803532 | 0.69 | ALDH1A1 (0.55) | ALDH1A1GLATP53TSHRHIF1A | |
| SCHEMBL10594378 | 0.67 | ALDH1A1 (0.45) | ALDH1A1GLATP53TSHRHIF1A | |
| SCHEMBL26437840 | 0.67 | ALDH1A1 (0.49) | ALDH1A1GLATP53TSHRHIF1A | |
| SCHEMBL11537725 | 0.67 | ALDH1A1 (0.37) | ALDH1A1GLATP53TSHRHIF1A | |
| SCHEMBL11517337 | 0.66 | ALDH1A1 (0.48) | ALDH1A1GLATP53TSHRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144340-A | ADRENERGIC BLOCKING AGENTS | DEUTSCHE GOLD UND SILBER- SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1979-03-13 | — | — | US | disclosed |